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Fakultät für Biologie, Chemie und Geowissenschaften

Entwicklungsbiologie – Prof. Dr. Gerrit Begemann

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Auswahl nach Jahren:

Köhler LHF, Reich S, Yusenko M, Klempnauer KH, Shaikh AH, Ahmed K, Begemann G, Schobert R, Biersack B. 2022. A New Naphthopyran Derivative Combines c-Myb Inhibition, Microtubule-Targeting Effects, and Antiangiogenic Properties. ACS Medicinal Chemistry Letters, Articles ASAP (Letter). doi: 10.1021/acsmedchemlett.2c00403 (abstract)

Zhouyao H, Zimmer AM, Fehsenfeld S, Liebenstein T, Richter DO, Begemann G, Eck P, Perry SF, Weihrauch D. 2022. Characterization of two novel ammonia transporters, Hiat1a and Hiat1b, in the teleost model system Danio rerio. J Exp Biol. 2022 Sep 20:jeb.244279. doi: 10.1242/jeb.244279. (abstract)

Köhler LHF, Reich S, Begemann G, Schobert R, Biersack B.2022. 2-Amino-4-aryl-5-oxo-4,5-dihydropyrano[3,2-c]chromene-3-carbonitriles with Microtubule-Disruptive, Centrosome-Declustering, and Antiangiogenic Effects in vitro and in vivo. ChemMedChem. 2022 May 18;17(10):e202200064. DOI: 10.1002/cmdc.202200064. Epub 2022 Mar 16. (open access)

Draut H, Liebenstein T, Begemann G. 2019. New insights into the control of cell fate choices and differentiation by retinoic acid in cranial, axial and caudal structures. Biomolecules. 2019 v9(12):860. DOI: 10.3390/biom9120860. Epub 2019 Dec 11. (open access)

Schmitt F, Kasparkova J, Brabec V, Begemann G, Schobert R, Biersack B. 2018. New (arene)ruthenium(II) complexes of 4‑aryl‑4H‑naphthopyrans with anticancer and anti-vascular activities. J Inorg Biochem. 2018 Jul;184:69-78. DOI: 10.1016/j.jinorgbio.2018.03.013. Epub 2018 Apr 5. (abstract)

Schmitt F, Subramaniam D, Anant S, Padhye S, Begemann G, Schobert R, Biersack B. 2018. Halogenated Bis(methoxybenzylidene)-4-piperidone Curcuminoids with Improved Anticancer Activity. ChemMedChem. 2018 Jun 6;13(11):1115-1123. DOI: 10.1002/cmdc.201800135. Epub 2018 Apr 23. (abstract)

Schmitt F, Gold M, Begemann G, Andronache I, Biersack B, Schobert R. 2017. Fluoro and pentafluorothio analogs of the antitumoral curcuminoid EF24 with superior antiangiogenic and vascular-disruptive effects. Bioorg Med Chem. Sep 1;25(17):4894-4903. DOI: 10.1016/j.bmc.2017.07.039. Epub 2017 Jul 21. (abstract)

Draut H, Rehm T, Begemann G, Schobert R. 2017. Antiangiogenic and toxic effects of genistein, usnic acid, and their copper complexes in zebrafish embryos at different developmental stages. Chemistry & Biodiversity. Mar;14(3). DOI: 10.1002/cbdv.201600302. Epub 2017 Mar 7. (abstract)

Blum N, Begemann G. 2015. Osteoblast de- and redifferentiation are controlled by a dynamic response to retinoic acid during zebrafish fin regeneration. Development 142:2894-2903. (abstract)

Blum N, Begemann G. 2015. Retinoic acid signaling spatially restricts osteoblasts and controls ray-interray organization during zebrafish fin regeneration. Development 142:2888-2893. (abstract) (PDF Pressemitteilung)

Offen N, Kang JH, Meyer A, Begemann G. 2013. Retinoic acid is involved in the metamorphosis of the anal fin into an intromittent organ, the gonopodium, in the green swordtail (Xiphoporus hellerii). PLoS ONE 8(10): e77580 (PDF).

Blum N, Begemann G. 2013. The roles of endogenous retinoid signaling in organ and appendage regeneration. Cellular and Molecular Life Sciences. doi:10.1007/s00018-013-1303-7.  Review (abstract)

Pittlik S, Begemann G. 2012. New sources of retinoic acid synthesis revealed by live imaging of an Aldh1a2-GFP reporter fusion protein throughout zebrafish development. Developmental Dynamics 241: 1205-1216.(abstract)

Blum N, Begemann G. 2012 Retinoic acid signaling controls the formation, proliferation and survival of the bastema during adult zebrafish fin regeneration. Development 139:107-116. (abstract)

Manousaki T, Feiner N, Begemann G, Meyer A, Kuraku S. 2011. Co-orthology of Pax4 and Pax6 to the fly eyeless gene: molecular phylogenetic, comparative genomic, and embryological analyses. Evolution & Development 13(5):448-459. (abstract)

Kikuchi K, Holdway JE, Major RJ, Blum N, Dahn RD, Begeman G, Poss KD. 2011. Retinoic acid production by endocardium and epicardium is an injury response essential for zebrafish heart regeneration. Developmental Cell 20(3):397-404. (abstract)

Gibert Y, Bernard L, Debiais-Thibaud M, Bourrat F, Joly JS, Pottin K, Meyer A, Retaux S, Stock DW, Jackman WR, Seritrakul P, Begemann G, Laudet V. 2010. Formation of oral and pharyngeal dentition in teleosts depends on differential recruitment of retinoic acid signaling. The FASEB Journal 24:3298-3309. (abstract)

Feiner N, Begemann G, Renz A, Meyer A, Kuraku S. 2009. The origin of bmp16, a novel Bmp2/4 relative, retained in teleost fish genomes. BMC Evolutionary Biology 9:277 (abstract)

Offen N, Meyer A, Begemann G. 2009. Identification of novel genes involved in the development of the sword and gonopodium in swordtail fish. Developmental Dynamics 238, 1674-1687.(abstract)

Offen N, Blum N, Meyer A, Begemann G. 2008. Fgfr1 signalling in the development of a sexually selected trait in vertebrates, the sword of swordtail fish. BMC Developmental Biology 8:98 (abstract).

Eibner C, Pittlik S, Meyer A, Begemann G. 2008. An organizer controls the development of the "sword", a sexually selected trait in swordtail fish. Evolution & Development 10(4):403-412. (abstract)

Begemann G. 2008. MicroRNAs and RNA interference in zebrafish development. Zebrafish. 5(2):111-9. Review (abstract)

Pittlik S, Domingues S, Meyer A, Begemann G. 2007. Expression of zebrafish aldh1a3 (raldh3) and absence of aldh1a1 in teleosts. Gene Expression Patterns 8(3):141-147. (abstract)

Gibert Y, Gajewski A, Meyer A, Begemann G. 2006. Induction and prepatterning of the zebrafish pectoral fin bud requires axial retinoic acid signaling. Development 133: 2649-2659. (abstract)

Hamade A, Deries M, Begemann G, Bally-Cuiff L, Genet C, Sabatier F, Bonnieu A and Cousin X. 2006. Retinoic acid activates myogenesis in vivo through Fgf8 signalling. Developmental Biology 289: 127-140. (abstract)

Gu W*, Gibert Y*, Wirth T, Elischer A, Bloch W, Meyer A, Steinlein OK and Begemann G. 2005. Using gene-history and expression analyses to assess the involvement of LGI genes in human disorders. Molecular Biology and Evolution 22: 2209-2216. (abstract)

Gibert Y, McMillan DR, Kayes-Wandover K, Meyer A, Begemann G, and White PC. 2005. Analysis of the very large G-protein coupled receptor gene (Vlgr1/Mass1/USH2C) in zebrafish. Gene 353: 200-206. (abstract)

Sanetra M, Begemann G, Becker MB, Meyer A. 2005. Conservation and co-option in developmental programmes: the importance of homology relationships. Frontiers in Zoology 2: 15. Review (Open Access)

Keegan BR, Feldman JL, Begemann G, Ingham PW and Yelon D. 2005. Retinoic acid signaling restricts the cardiac progenitor pool. Science 307:247-249. (abstract)

Begemann G, Marx M, Mebus K, Meyer A and Bastmeyer M. 2004. Beyond the neckless phenotype: influence of reduced retinoic acid signaling on motor neuron development in the zebrafish hindbrain. Developmental Biology 271: 119-129. (abstract)

Zauner H*, Begemann G*, Mari-Beffa M and Meyer A. 2003. Differential regulation of msxgenes in the development of the gonopodium, an intromittent organ, and of the sword, a sexually selected trait of swordtail fishes (Xiphophorus). Evolution & Development 5 (5):466-477. (abstract)

 "What The Papers Say", a comment by Adam S. Wilkins in BioEssays

Begemann G, Gibert Y, Meyer A and Ingham PW. 2002. Cloning of zebrafish T-box genes tbx15 and tbx18 and their expression during embryonic development . Mech. Dev. 114(1-2):137-141. (abstract)

Gibert Y, Begemann G. 2002. Variations on a "T": orchestration of T-box signalling in development. Trends in Genetics 18:615-616. Meeting Report

Begemann G, Schilling TF, Rauch, GJ, Geisler, R and Ingham PW. 2001. The zebrafish neckless mutation reveals a requirement for raldh2 in mesodermal signals that pattern the hindbrain. Development 128:3081-94. (abstract)

Begemann G, Meyer A. 2001. Hindbrain patterning revisited: timing and effects of retinoic acid signalling. BioEssays 23:981-86. Review (abstract)

Begemann G, Ingham PW. 2000. Developmental regulation of Tbx5 in zebrafish embryogenesis. Mech. Dev. 90(2):299-304 (abstract)

Artero R, Prokop A, Paricio N, Begemann G, Pueyo I, Mlodzik M, Perez-Alonso M, Baylies MK. 1998. The muscleblind gene participates in the organization of Z-bands and epidermal attachments of Drosophila muscles and is regulated by Dmef2. Dev Biol. 195(2):131-43. (abstract)

Begemann G*, Paricio N*, Artero R, Kiss I, Perez-Alonso M, Mlodzik M. 1997. Muscleblind, a gene required for photoreceptor differentiation in Drosophila, encodes novel nuclear Cys3His-type zinc-finger-containing proteins. Development 124(21):4321-31. (abstract)

Begemann G, Michon AM, v d Voorn L, Wepf R, Mlodzik M. 1995. The Drosophila orphan nuclear receptor seven-up requires the Ras pathway for its function in photoreceptor determination. Development 121(1):225-35. (abstract)

Book Chapters and Literature Reviews/Commentaries:

Begemann G. 2010. Die Evolution von Entwicklungsprozessen: Was wir von Fischen über die Evolution lernen können. In: MNU-Dokumentationen / 14. Fachleitertagung Biologie, Verlag Klaus Seeberger (2011) (Deutscher Verein zur Förderung des mathematischen und naturwissenschaftlichen Unterrichts e.V.)

Begemann G. 2010. Mit Durchsicht zum Erfolg: Zebrafische als Modell in der Forschung. In: Biologie für Einsteiger. Prinzipien des Lebens verstehen. By Olaf Fritsche, Spektrum Akademischer Verlag. (publisher)

Begemann G, Zebrafish (4 times per year, 2005-2011): Literature Review and Commentary.

Begemann G. 2005. Retinoic acid signalling controls anteroposterior patterning of the zebrafish hindbrain. In: Key Experiments In Practical Developmental Biology. Editors: M. Mari-Beffa, J. Knight. Cambridge University Press. (publisher)

Embryonalentwicklung und genetische Methoden im Zebrafisch - Online Companion Site: Lehrbuch der Genetik. By: Wilhelm Seyffert, 2003, Spektrum Akademischer Verlag. (inaktiv)

Verantwortlich für die Redaktion: Univ.Prof.Dr. Gerrit Begemann

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